I-Docetaxel lichiza elisetyenziswa ngokubanzi ukunyanga ii-cancer ezahlukeneyo, ezisebenza ngokuphazamisa izakhiwo ze-microtubule kwiiseli zomhlaza.Olu phawu lwenza i-docetaxel ibe sisixhobo esinamandla kunyango lwe-tumor, ngakumbi kwiimeko apho ezinye iindlela zonyango zingasebenzi.
I.Indlela yokuSebenza:Ukuphazamisana neMicrotubules kwiiSeli zoMhlaza
DocetaxelUkwiklasi ye-taxane yee-chemotherapeutic agents, ezisebenza ngokuchaphazela izakhiwo ze-microtubule kwiiseli, ngaloo ndlela zichaphazela ukwahlukana kweeseli. umsebenzi oqhelekileyo wezi microtubules, ezinokuthi zithintele okanye zicothise ukukhula kunye nokusasazeka kweeseli zomhlaza.
II.Ukunyangwa kwemiHlaza emininzi
Umhlaza wamabele: IDocetaxel idlala indima ebalulekileyo kunyango lomhlaza wamabele, ngakumbi kwiimeko apho umhlaza uye we-metastas kwezinye iisayithi (kwinqanaba eliphambili) kwaye ezinye iindlela zonyango ziye zasilela ukunika iziphumo ezanelisayo.Inokunceda ukulawula ukuqhubeka komhlaza wamabele.
Umhlaza wemiphunga yeSeli engeNcinane (NSCLC): I-NSCLC yenye yezona ntlobo zixhaphakileyo zomhlaza wemiphunga, kwaye i-docetaxel iqhele ukusetyenziswa ngokudityaniswa namanye amachiza echemotherapy ukunyanga iimeko ezikwinqanaba eliphezulu okanye apho umhlaza usasazeke kwezinye iindawo. unyango oludibeneyo lunokunceda ukucothisa ukukhula kwamathumba.
I-Prostate Cancer: I-Docetaxel isetyenziswa ngokuqhelekileyo kunyango lomhlaza we-prostate, ngakumbi kwiimeko apho umhlaza uye waqhubela phambili ukuya kwinqanaba eliphezulu okanye ezinye iindlela zonyango ziye zaphelelwa amandla.Ukudibanisa kunye namanye amachiza kunokuphucula amathuba onyango oluyimpumelelo.
Umhlaza Wesisu (Umhlaza Wesisu):Docetaxelikwasetyenziswa kunyango lomhlaza wesisu, ngakumbi kwiintlobo ezithile zomhlaza wesisu. Idla ngokudityaniswa namanye amachiza ukunika unyango olubanzi.
Isishwankathelo,docetaxel, iyeza le-chemotherapy elithintela ukuhlukana kweeseli ngokuphazamisa izakhiwo ze-microtubule kwiiseli zomhlaza, libonise ukusebenza kakuhle kunyango lweentlobo ezininzi zomhlaza.Nangona kunjalo, inokuhamba kunye noluhlu lwemiphumo emibi, ngoko kufuneka isetyenziswe phantsi ukubeka iliso kwiingcali zonyango ukuqinisekisa isiphumo sonyango esifanelekileyo kunye nokhuseleko lwesigulane.
Qaphela:Ukusebenza okunokwenzeka kunye nezicelo ezikhankanywe kweli nqaku zithathwe kuncwadi olupapashwe esidlangalaleni.
Ufundo olwandisiweyo: IYunnan Hande Biotech Co., Ltd.igxile ekuvelisweni kwezinto ezikrwada ze-docetaxel ngaphezulu kweminyaka engama-20, kwaye kuphela komvelisi ozimeleyo wezixhobo eziphuma kwisityalo esichasene nomhlaza idocetaxel evunywe ziiarhente ezilawulayo ezifana ne-US FDA, I-EDQM yaseYurophu, iTGA yaseOstreliya, iCFDA yamaTshayina, iIndiya, kunye neJapan.
Ixesha lokuposa: Oct-26-2023