Cabazitaxel Cas 183133-96-2 uMvelisi weCabazitaxil

Cabazitaxel Cas 183133-96-2 uMvelisi weCabazitaxil Umfanekiso ofakiweyo
  • Cabazitaxel Cas 183133-96-2 uMvelisi weCabazitaxil

Inkcazelo emfutshane:

I-Carbataxel yinto yekhemikhali esetyenziselwa ukwenza amachiza okulwa nomhlaza.ICarbataxel ngumgubo omhlophe okanye omhlophe ophantse unganyibiliki emanzini, kodwa unyibilika kwi-ethanol.Indlela yayo yokulwa nomhlaza kunye neempawu zifana ne-docetaxel, kwaye ingeyeklasi ye-anti-microtubule drug.Ngokusebenzisa ukudibanisa kunye ne-tubulin, ukukhuthaza ukuhlanganisana kwayo kwii-microtubules, kwangaxeshanye kunokuthintela ezi ziqokelele i-microtubule disassembly, ezizinzisa ii-microtubules, ngaloo ndlela zithintela i-cell mitosis, kunye nokusebenza kweeseli ze-interphase (interphasecellularfunctions).


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi ngeMveliso

Igama:Cabazitaxel

Inombolo yeCAS:183133-96-2

Ifomula yemichiza:C45H57NO14

Iinkcukacha:99%

Umbala:umgubo omhlophe okanye omhlophe

Umthombo:ISemi-synthesized nge-10-DAB

Uhlobo:APIs

Isiphumo

I-Carbataxel yi-taxane derivative esebenza njenge-microtubule inhibitor, ebophelela kwi-tubulin kunye nokukhuthaza ukuhlanganiswa kwayo kwii-microtubules, ngelixa ikhusela ukuchithwa kwezi microtubules ezidibeneyo kunye nokuzinzisa i-microtubules.Olu thintelo lubangela ukudityaniswa kwee-microtubules kunye nokuyeka ukwahlukana kweeseli, ngaloo ndlela kumisa umjikelo weseli kunye nokuthintela ukwanda kwethumba.Ngoko ke, i-carbataxel isetyenziselwa ukulungiswa kwezidakamizwa ezichasayo, zinefuthe elihle lokulwa nomhlaza, kwaye zingasetyenziselwa ukunyanga izifo ezahlukeneyo zebhaktheriya.Ngokukodwa, i-carbataxel isetyenziswe ngokubanzi ukunyanga i-prostate, ibele, i-ovarian, imiphunga, kunye nezinye ezininzi iintsholongwane zomhlaza, kunye nosulelo lwebhaktheriya, kuquka i-sinusitis, i-bronchitis, i-pneumonia, izifo ze-urinary, izifo zamehlo, izifo zesikhumba, kunye ne-otitis media.

Iinkonzo zethu

1.Iimveliso:Ukubonelela ngomgangatho ophezulu, izicatshulwa zezityalo ezisulungekileyo, imathiriyeli ekrwada yamayeza, kunye nabaphakathi bamayeza.

2.Iinkonzo zobugcisa:Izicatshulwa ezenziwe ngokwezifiso ezineenkcazo ezizodwa ngokweemfuno zabathengi.

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