ILigustrazine Ligusticum chuanxiong ikhupha imathiriyeli ekrwada yamayeza

Ulwazi ngeMveliso

I-Ligustrazine yi-bioactive component ekhutshwe kwi-Ligusticum chuanxiong, iyeza elisetyenziswa ngokubanzi laseTshayina.Inokuthintela ukudityaniswa kweplatelet, iphucule i-vasodilation, inyuse ukuhamba kwegazi kwi-cerebral kunye ne-neuroprotective effect.I-Ligustrazine injection isetyenziswe ngokubanzi kunyango lwe-ischemic stroke, isifo senhliziyo, isifo sesifo sikashukela kunye ne-osteoarthritis yamadolo e-China.I-Ligustrazine iphinde ihlolwe njengonyango lwezonyango kwizilonda zoxinzelelo, njenge-agent yokulondoloza izigulane ezine-non-Hodgkin's lymphoma, kunye nonyango lwe-asthma ye-bronchial kunye ne-vertebrobasilar insufficiency.
1, Iimpawu zeLigustrazine
I-Ligustrazine yikristale ye-acicular engenambala kunye ne-melting point ye-80-82 ° (ukuzimisela kwe-microscopic) kunye neqondo elibilisayo le-190 °.Inephunga elikhethekileyo, i-hygroscopicity kunye ne-sublimation elula.Inyibilika ngokulula emanzini ashushu kunye ne-petroleum ether, i-chloroform kunye ne-dilute hydrochloric acid, i-soluble kancinane kwi-ether kwaye ayinyibiliki emanzini abandayo.
2, Isiphumo seLigustrazine
1. Umphumo entliziyweni
2. Ukwandisa ukuhamba kwe-coronary
3. Yandisa imithambo yegazi ejikelezayo kwaye unciphise uxinzelelo lwegazi
4. Ukuphucula ukujikeleza kwecerebral
5. Inhibit platelet aggregation kunye ne-antithrombotic
6. Impembelelo kwinkqubo yomchamo
7. Ukuphucula i-microcirculation
8. Impembelelo kwinkqubo yokuphefumla
9. Anti tumor
10. Ukuphucula ukusebenza komzimba
11. Ukunqanda ukwenzakala kwemitha kunye nokwazisa ngemitha
3, Imo yemveliso yeLigustrazine
I-Dimethylpyrazine yalungiswa ngokucondelwa kwe-butanone kunye ne-ethyl nitrite ukuvelisa i-dimethylglyoxime, eyathi yancitshiswa kwaye yahamba ngebhayisikili.Imveliso ye-cyclization reaction ihlanjululwa ngumphunga, kwaye i-distillate ipholile, i-crystallized kwaye ihluzwe ukufumana imveliso ekrwada ye-tetramethylpyrazine.Ukuhlaziywa kwamanzi kunye ne-activated carbon decolorization zisetyenziselwa ukucokisa.Xa ulungisa i-hydrochloride yayo, isisombululo se-ethanol esiqulethe i-15% - 20% ye-hydrogen chloride inokongezwa kwi-dropwise kwi-acetone ukwenza ityuwa.
4. Iinkalo zesicelo zeLigustrazine
1. Ishishini lamachiza: ukuveliswa kweziyobisi.
2. Ishishini lokutya: lisetyenziswa njenge-agent yencasa, isiphuculi sencasa yesiselo esinxilisayo, i-agent yencasa kunye neyongezelelo yecuba.

IiParameters zeMveliso

IPROFAYILE YEKHAMPANI
Igama lemveliso	ligustrazine
CAS	1124-11-4
Ifomula yeMichiza	C8H12N2
Birandi	Hkwaye
Mumenzi	Yunnan Hande Bio-Tech Co., Ltd.
Cukuphuma	Kunming,Chayi
Isekiwe	1993
BINGCACISO YEASIC
Izithethantonye	I-Tetramethylpyrazine;2,3,5,6-tetramethylpyrazine;I-Pyrazine, i-tetramethyl-;
Ulwakhiwo
Ubunzima	136.19400
HS Ikhowudi	N / A
UmgangathoSukucaciswa	Inkcazo yeNkampani
CIzaziso	N / A
Isivavanyi	Customized ngokweemfuno zabathengi
Imbonakalo	Ikristale yeacicular engenambala
Indlela yokutsalwa	irhizome ye chuanxiong
Ubunakho boNyaka	Customized ngokweemfuno zabathengi
Iphakheji	Customized ngokweemfuno zabathengi
Indlela yoVavanyo	N / A
Ulungiselelo	Ezininziuthuthos
PaymentTerms	T/T, D/P, D/A
Oapho	Yamkela uphicotho lwabathengi ngalo lonke ixesha;Ukunceda abathengi ngobhaliso lolawulo.

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