I-paclitaxel yendalo ye-paclitaxel apis iyeza le-anticancer apis

Ulwazi ngeMveliso

Igama:Paclitaxel

Inombolo yeCAS:33069-62-4

Ifomula yemichiza:C47H51NO14

Iinkcukacha:99%-102%

Umbala:umgubo omhlophe okanye phantse omhlophe

Umthombo:Taxus yunnanensis,Taxus chinensis

Uhlobo:APIs

Indima ye-paclitaxel yendalo

I-1, inqanda ukwahlukana kweeseli ze-tumor kunye nokwanda: i-paclitaxel yendalo inokuphazamisa inkqubo yokwahlula kweeseli kunye nokwanda, okubangela ukuba iiseli zomhlaza zingakwazi ukukhula nokuzala ngokuqhelekileyo, ngaloo ndlela zivimbela ukuphuhliswa nokusasazeka kwezicubu.

2, bangela i-apoptosis yeseli ye-tumor: I-paclitaxel yendalo inokubangela inkqubo ezonakalisayo eyenza iiseli zomhlaza zife ngokwazo, ezaziwa ngokuba yi-apoptosis.Le ndlela inokubulala ngokufanelekileyo iiseli zomhlaza, ukunciphisa umthamo wethumba, kunye nokunciphisa iimpawu zezigulane.

3. Ukuthintela i-angiogenesis ye-tumor: ukukhula kunye nokusasazeka kwamathumba kufuna imithambo yegazi emitsha ukubonelela izondlo.I-paclitaxel yendalo inokuthintela umsebenzi we-vascular endothelial growth factor, ngaloo ndlela ithintele ukubunjwa kwemithambo yegazi ye-tumor, inqumle unikezelo lwezondlo lwamathumba, kwaye lukhokelela ekufeni kweeseli zethumba.

Iinkonzo zethu

1.Iimveliso:Ukubonelela ngomgangatho ophezulu, izicatshulwa zezityalo ezisulungekileyo, imathiriyeli ekrwada yamayeza, kunye nabaphakathi bamayeza.

2.Iinkonzo zobugcisa:Izicatshulwa ezenziwe ngokwezifiso ezineenkcazo ezizodwa ngokweemfuno zabathengi.