Njengechiza elinokuthi lithintele i-COVID_19,cepharanthinesesona sithako sisebenzayo sitsalwa kuStephania, iyeza lemveli lamaTshayina.Iyeza laseTshayina lelungelo elilodwa lomenzi wechiza lidweliswe eTshayina nakumazwe aphesheya ngaphezulu kweminyaka engama-40.
Ngomhla we-10 kuMeyi, 2022, izazinzulu zaseTshayina zafumanisa unyango lwe-covid_ 19 amachiza amatsha afumene amalungelo awodwa omenzi wechiza wesizwe.Ingcaciso yelungelo elilodwa lomenzi wechiza ibonisa ukuba i-10μM(micromol/L) cepharanthine inhibisa ukuphindaphindwa kwe-coronavirus ngamaxesha angama-15393.
Nje ukuba luphume olu lwazi, bekuchwayitisa kakhulu phambi kokuba i-COVID 19 ingasonjululwa ngokufanelekileyo. Nangona i-cepharanthine isekwinqanaba lophando lwamachiza kunye nophuhliso kwaye ingekasetyenziswa ngokusemthethweni kuqeqesho lwezonyango, ikwaziindaba ezimnandi kakhulu kubo. imeko yangoku ye-Covid 19. Ngapha koko, ngokweengxelo zemithombo yeendaba, abanye abaphengululi baseMelika baye bapapasha amaphepha kwisayensi kwaye baqinisekisa ukuba idatha yophando ye-cepharanthine ingcono kune-paxlovid, evunyiweyo ukuba idweliswe. Okwangoku, umntu waseCanada. ishishini lamayeza liqhagamshelane ne-US FDA ukwenza uphononongo lolingo lwezonyango kunyango lwe-COVID-19 nge-Cepharanthine. Kuyathenjwa ukuba kuya kubakho inkqubela phambili kwi-R&D kunye nokusetyenziswa kwezonyango kweli chiza kungekudala.
I-Cepharanthine(CEP) yi-alkaloid eyenzeka ngokwemvelo evela ku-Stephania cepharantha Hayata kwaye ibonakaliswe ukuba ine-anti-inflammatory, i-antioxidative, i-immunomodulating, i-antiparasitic, kunye ne-antiviral properties.
Amandla ayo onyango njengearhente ye-antiviral ayikaze ibaluleke ngakumbi kunokulwa i-COVID-19 ebangelwa sisifo esiqatha sokuphefumla isifo se-coronavirus yohlobo 2 (SARS-CoV-2) intsholongwane.
Phakathi kwabanini bamalungelo awodwa omenzi wechiza abambalwa, sinamalungelo awodwa abenzi anxulumene nawoI-Cepharanthine.
IYunnan Hande Bio-tech Co.,Ltd.ngumenzi kunye nomthengisi onamava angama-28+ ekutsalweni okuphezulu kunye nokwahlulwa kwezityalo.I-Cepharanthineekuqaleni kuka-Agasti 2011.I-patent yethu ichaza ngokucacileyo indlela i-stephanine ekhutshwe ngayo.Ukuba ufuna i-Cepharanthine kulo mbandela, unganqikazi, nceda uqhagamshelane nathi ngokukhawuleza.
Ixesha lokuposa: May-16-2022