Iimpawu ze-Albumin-bound paclitaxel

I-Paclitaxel lichiza elitsha le-anti microtubule, elisetyenziswa ngokubanzi kunyango lomhlaza we-ovarian, umhlaza webele, umhlaza wemiphunga, amathumba entloko kunye nentamo, umhlaza womqala, umhlaza wesisu kunye ne-sarcoma yezicubu ezithambileyo. ngokuphononongwa okuqhubekayo kweerhafu kunye nokuphuculwa okuqhubekayo kweteknoloji yokulungiselela.Makhe sijonge iimpawu ze-Albumin-bound paclitaxel.

I-albumin-bound paclitaxel: i-nanoparticles eyenziwe nge-paclitaxel kunye ne-albumin ye-serum yabantu nge-high-pressure vibration teknoloji, i-albumin molecule kunye neeamolekyuli ezisixhenxe ze-paclitaxel zidityanisiwe, kunye nendima ye-albumin receptor Gp60 kwi-membrane yeseli kunye ne-cysteine ​​​​esityebi esine-acidic secretory albumen ( SPARC)kwithishu yethumba isetyenziselwa ukukhuthaza iyeza ukuba lingene kwiiseli zethumba kwaye linyuse isiphumo sechemotherapy.

1, Ukhuseleko

I-albumin-bound paclitaxel:ayikho i-cosolvent polyoxyethyl ioli ye-castor efunekayo, enokunyusa ngokukhuselekileyo idosi ye-paclitaxel, ifinyeze ixesha lokungena, kwaye akukho nyango lufunekayo.

2. Unyango lwangaphambili

I-albumin-bound paclitaxel ayifuni nyango lwangaphambili ukuthintela ukuchasana nokwaliwa phambi kokulawulwa.

3. Iimpendulo ezingalunganga

I-Albumin-bound paclitaxel kunye ne-paclitaxel liposomes: Ngenxa yokuphuculwa kobuchwepheshe bokulungiselela, akukho mfuneko yokongeza izinto ezincedisayo ezifana ne-polysoxyethyl castor oil, i-polysorbate 80, i-ethanol epheleleyo, njl., kwaye ukhuseleko lweziyobisi luphuculwe kakhulu.

4. Iimpawu

I-Albumin-bound-bound paclitaxel:uncwadi olufanelekileyo lunika ingxelo yokuba iyeza layo elinye kunye nerejimeni edibeneyo lukhetho lonyango lomhlaza webele ogqithisayo oqhubeka ngokukhawuleza okanye ongaphumeleliyo kunyango lwemigca emininzi.Ikwabonisa ukusebenza kakuhle kwe-paclitaxel kunye nomhlaza webele ongathandekiyo ophindwe kathathu. ngaphambili iphathwe nge-paclitaxel, kwaye iziphumo ebezingalindelekanga ziyanyamezeleka.

Qaphela:Ukusebenza okunokwenzeka kunye nezicelo eziveliswe kweli nqaku zonke zivela kuncwadi olupapashiweyo.

I-Yunnan Hande Biotechnology Co., Ltd ibigxile ekuvelisenipaclitaxel APIngaphezulu kweminyaka engama-20, kwaye ngomnye wabavelisi behlabathi abazimeleyo be-paclitaxel API, ichiza eliphuma kwisityalo elichasene nomhlaza, elivunywe yi-US FDA, i-European EDQM, i-Australian TGA, iCFDA yamaTshayina, iIndiya, iJapan kunye nezinye iiarhente ezilawula ilizwe. .I-Hande ayinikezeli kuphela umgangatho ophezulupaclitaxel imathiriyeli ekrwada,kodwa kunye neenkonzo zophuculo lobugcisa ezinxulumene ne-paclitaxel formulation.Ngolwazi oluthe kratya, nceda uzive ukhululekile ukuqhagamshelana nathi ku-18187887160.