Ukongeza kuthintelo olunokwenzeka lwe-COVID 19, zithini iziphumo zeCepharanthine?

I-Cepharanthine, iyeza laseTshayina elingummangaliso, yindalo ye-isoquinoline alkaloid ekhutshwe kwi-Stephania.cepharanthaHayita.

Ngo-2022, waba ngummeli wethemba kwaye wayexhalabile ngumntu wonke, enethemba lokuba ngumbulali osebenzayo ukusombulula i-covid 19. Ukongeza ekubeni sisityalo esithandwayo kulo nyaka, i-cepharanthine lichiza elisetyenziswa eJapan ukusukela ngo-1950s ukunyanga. izifo ezahlukeneyo ezibukhali nezingapheliyo, kubandakanya i-leukopenia, ukulunywa yinyoka, umlomo owomileyo kunye nokulahleka kweenwele.

Ke iCepharanthine ingasetyenziswa phi?

● Umsebenzi we-Antitumor

I-Cepharanthine ine-antitumor effect.I-Cepharanthine yodwa inokudlala indima ye-antitumor ngokuthintela ukwanda kweeseli ze-tumor kunye nokuphucula ukukhuseleka komzimba.Okuthembisayo ngakumbi kukuba i-Cepharanthine idibene neziyobisi ze-chemotherapeutic inokuphucula ukusebenza kwe-chemotherapy ngokunciphisa ukunyanzeliswa kweziyobisi. iiseli.Iyona ndlela iphambili inokuthi i-stephanine inokunyusa ukuqokelela kwamachiza e-anticancer kwiiseli ngokuphazamisa umsebenzi we-plasma membrane.

●Amayeza okuthomalalisa iintlungu

I-Cepharanthineingasetyenziselwa i-analgesia yamayeza esintu kwaye ikhulule iintlungu zezigulane.

● Ukukhuthaza ukwanda kwe-leukocyte

I-Cepharanthine, iyeza lokwanda kwe-leukocyte, inokukhuthaza ukwanda kwezicubu zomongo kunye nokwandisa i-leukocytes.Indlela yayo kukukhuthaza ukwanda kwezicubu zomongo wethambo, okukhokelela ekwandeni kwe-leukocytes.Isetyenziselwa i-agranulocytosis ebangelwa yi-tumor chemotherapy kunye ne-radiotherapy kunye ne-leukopenia ebangelwa zezinye izizathu.

Ukongeza, i-CEP idityaniswe namachiza e-antitumor iyacetyiswa ukunyanga i-immunosuppression kunye ne-thrombocytopenia ebangelwa yi-radiotherapy kunye ne-chemotherapy, kwaye akukho ziphumo bezingalindelekanga ezicacileyo. , enokuthintela usulelo lwe-SARS, i-HIV, i-HSV-1, i-covid-19 kunye nentsholongwane ye-Ebola, kwaye inyange izifo ezahlukeneyo ze-autoimmune kunye nokwaliwa.

NokubaI-Cepharanthineunokufumana iindaba ezimnandi kwindlela yokuthintela kunye ne-antiviral kungekudala, yile nto sijonge phambili kuyo ngoku, kwaye ikwangqina impumelelo yamayeza emveli aseTshayina.I-Yunnan hande ibonelela ngenkonzo enyanisekileyo kunye neCepharanthine ebalaseleyo.