Siyazi ukuba i-Paclitaxel ayinyibiliki emanzini, ke i-Paclitaxel Injection yesiko isebenzisa ioyile ye-castor ukunyibilikisa i-Paclitaxel, ezisa iingxaki ezininzi:
1.Iziyobisi azijoliswanga kwiithumba.Inani elikhulu lamachiza lichaphazele umzimba wonke wezigulane.Zonke iindawo kunye namalungu omzimba aphethwe ngumonakalo oyityhefu.Iziphumo ebezingalindelekanga zechemotherapy kunye neziyobisi zinamandla ngokwentelekiso;
2.Ngenxa yetyhefu kunye neziphumo ebezingalindelekanga kuwo wonke umzimba, idosi yeziyobisi ilinganiselwe, nto leyo ekhokelela ekubeni ezinye izigulane zingasasebenzi emva kwexesha lonyango kwaye ziphulukane nesicwangciso sonyango olulandelelweyo;
I-3.I-oyile ye-Castor kulula ukubangela i-allergies, ngoko ke phambi kwe-chemo nganye, isigulane kufuneka siphathwe kwangaphambili ngeentlobo ezahlukeneyo zamachiza ukuthintela ukungahambi kakuhle.
As Paclitaxeliselelona chiza lisebenzayo, elibanzi-elibanzi elichasene nomhlaza kwihlabathi, yinto engenakuthintelwa kwiifomu zedosi entsha nezingcono zokutshintsha kancinci kancinci iifomu zedosi yokuqala.
Ngokohlalutyo lwedatha yeklinikhi kunye nentengiso yentengiso, ezona ndlela zimbini zinokubakho zedosi zingezantsi:
1.Paclitaxel(I-Albumin-Bound yokuTofwa)
2.Paclitaxel Polymeric Micelles for Injection
Apha makhe sijonge kwizinto eziluncedo kwezi fom 2 zedosi.
Njengoko sibona kwitheyibhile, ezi fomu zimbini zedosi zineenzuzo ezicacileyo zeklinikhi, ke zisebenza kakuhle emva kokuba zithengisiwe, zide zithathe indawo yentengiso yemveli yePaclitaxel Injection.
I-Paclitaxel(I-Albumin-Bound yokuTofwa)
Ngenxa yeenzuzo zayo zokusebenza kakuhle, ukusetyenziswa ngokulula kunye nokhuseleko oluphezulu, i-Paclitaxel (i-Albumin-Bound ye-Injection) ikhawuleze yathatha indawo yesabelo semarike yenaliti ye-paclitaxel yesintu, kwaye isetyenziswa ngokubanzi kwizalathiso zamathumba amaninzi emva kokuba zibandakanyiwe kuluhlu lwe-inshorensi yezonyango yesizwe.
I-Albumin paclitaxel yaphuhliswa njenge-Abraxane ye-BMS, kwaye umthamo wayo wokuthengisa wawuyi-0.9 yeebhiliyoni zeedola ngo-2021.
Ngo-2021, ukuthengiswa kwe-Paclitaxel (i-Albumin-Bound ye-Injection) ekupheleni kwamaziko onyango karhulumente e-China yasondela kwi-4 yeebhiliyoni zeeyuan (572 yezigidi zeedola), ngokukhula okungaphezulu kwe-10% kwisiqingatha sokuqala sika-2022. (abemi yaseTshayina: 1.4 yebhiliyoni)
I-Paclitaxel(i-Albumin-Bound ye-Injection) iba yeyona fomula idumileyo ye-Paclitaxel.Yamkelwa ngokubanzi zizigulana, oogqirha kunye noorhulumente ngenxa yeenzuzo zayo kunye nexabiso elifikelelekayo.
Isitofu sePaclitaxel Polymeric Micelles
I-Paclitaxel Polymeric Micelles Injection lichiza elitsha eliphuculweyo eliphuhliswe ngokuzimeleyo, elingeyo anda, kwaye alinakhuphisani okwangoku.
Xa kuthelekiswa ne-albumin paclitaxel, inokusebenza kakuhle, ukhuseleko, ukunyamezela iziyobisi kunye nezinye izikhombisi, iinzuzo zokunyuswa kwezonyango, kunye nendawo enkulu yenzuzo. Ngoko ke, isanda kuvunywa ukuba ithengiswe isiqingatha sonyaka, kwaye ifikelele kwingeniso eyi-60 yezigidi zeeyuan. .
Ukuza kuthi ga ngoku le kuphela kwePaclitaxel Polymeric Micelles Injection evunyiweyo kwihlabathi liphela, kodwa iinkampani ezimbalwa zamayeza zikwinkqubo yeR&D kunye nolingo lwezonyango kumazwe ahlukeneyo.
I-Albumin kunye nee-micelles zithwala ngokugqibeleleyo i-molecule encinci iziyobisi ezinganyibilikiyo.EmvaPaclitaxel, zinokusetyenziswa kwakhonaDocetaxel,Cabazitaxelkunye namanye amachiza anganyibilikiyo.Ixabiso lemarike eliziswe bubuchwephesha likhulu kakhulu.
I-Hande Bio-Tech ibonelela ngephakheji epheleleyo yeukudluliselwa kobugcisakwezi fom 2 zedosi, ukuxhasa iprojekthi yakho yexabiso ukufumana imvume yorhwebo ngokukhawuleza kakhulu kunezinye.
Qhagamshelana nathi ukuze wazi ngakumbi, ithuba inokuba lelakho.
Ixesha lokuposa: Nov-29-2022