Ukusebenza kunye nendima ye-paclitaxel

I-Paclitaxel ivela kwi-Taxus chinensis kwaye yeyona nto yakuqala ifunyenwe inesiphumo sokuthintela kwiiseli zethumba.Ubume be-paclitaxel buyinkimbinkimbi, kwaye ukusetyenziswa kwayo kwezonyango kubonakaliswa ikakhulu kunyango lomhlaza wamabele, umhlaza wemiphunga kunye nomhlaza wesibeleko.Paclitaxeli-metabolite yesibini ekhutshwe kwi-bark ye-Taxus chinensis yi-American chemist, ene-anti-tumor effect.Makhe sijonge ukusebenza kunye nendima ye-paclitaxel.

Ukusebenza kunye nendima yepaclitaxel

1. Impembelelo ye-Anti-tumor

I-Paclitaxel yi-anti-microtubule antitumor drug.I-Paclitaxel inokukhuthaza indibano ye-microtubule ngokukhuthaza i-polymerization ye-spinosomal tubulin subunits, nakwii-mediators ezifunekayo kwindibano eqhelekileyo ye-microtubule (efana ne-GTP, i-guanosine triphosphate, njl.)., njl.) Kwakhona kunokuba nalo mphumo, okubangela ukubunjwa kwe-microtubules engasebenziyo, ezinzileyo.

2. Isiphumo sokulwa nomhlaza

I-Paclitaxel ineempembelelo ze-anticancer kwimigca yeseli ye-sarcoma eyingozi, i-leukemia kunye ne-melanoma eyingozi.I-Paclitaxel ikwalichiza lokuqala labasetyhini abanomhlaza webele kunye nomhlaza wesibeleko.I-Paclitaxel inokubophelela kwi-microtubules, enokuthi "ikhenkce" kwaye ithintele ukuhlukana kweechromosomes ngexesha lokwahlula kweeseli, ezinokubulala ngokukhawuleza iiseli zomhlaza.

3. Unyango lwe-rheumatoid arthritis

Uphononongo lubonise ukuba i-paclitaxel yamkelwe yi-FDA kunyango lwe-rheumatoid arthritis, kunye nejeli ye-paclitaxel luyilo olusentloko.paclitaxel kunyango lwe-rheumatoid arthritis.

Qaphela: Ukusebenza okunokwenzeka kunye nokusetyenziswa okuchazwe kweli nqaku kuthathwe kuncwadi olupapashiweyo.

Ufundo olwandisiweyo:I-Yunnan Hande Biotechnology Co., Ltd. sele igxile kwimveliso ye-paclitaxel iminyaka eyi-28.Ngumvelisi wokuqala ozimeleyo wehlabathi we-anticancer drug paclitaxel evunywe yi-US FDA, i-European EDQM, i-Australian TGA, i-China CFDA, i-Indiya, i-Japan kunye nezinye ii-arhente ezilawulayo zelizwe.ishishini.Ukuba ufuna ukuthengaPaclitaxel API,nceda uqhagamshelane nathi kwi-intanethi.