I-Paclitaxel, njengechiza lokuqala lechemotherapy elikhutshwe kwizityalo zendalo, iselinye lamachiza aqhelekileyo kwi-tumor chemotherapy kude kube namhlanje.Paclitaxellichiza lendalo elichasene nethumba elikhutshwe kwizityalo ze taxus, kwaye indlela yokusebenza kwayo kukukhuthaza ukuhlanganiswa kwe-microtubule ukuthintela i-tumor cell mitosis. kwimarike yamachiza yamazwe ngamazwe.I-Paclitaxel ihlukaniswe kwi-paclitaxel yendalo kunye ne-semi synthetic paclitaxel.Makhe sijonge indima ye-10-Dab Semi-Synthetic Paclitaxel kwisicatshulwa esilandelayo.
10-Dab Semi-Synthetic Paclitaxelis a semi synthetic paclitaxel derivative with pharmacological activities ezifana ne-paclitaxel yendalo.I-Paclitaxe lichiza elisebenzayo lokulwa nomhlaza, nelinokusetyenziswa ukunyanga iintlobo ngeentlobo zomhlaza, ezinjengomhlaza wamabele, umhlaza wesibeleko, umhlaza wemiphunga kunye nomhlaza wesisu.Ulungiselelo. ye-precursor ye-10-DAB ye-paclitaxel ngokusebenzisa iindlela ze-semi synthetic inokunyusa isivuno kunye nokucoceka kwe-paclitaxel, ukunciphisa iindleko zemveliso, kwaye yenze i-paclitaxel igcineke ngakumbi kwaye ibe yezoqoqosho. kwiiseli ezithile zethumba.
10-Dab Semi-Synthetic Paclitaxelingenza imisebenzi emininzi kunye neziphumo, kungekuphela nje njengemveliso ephakathi kwiyeza, kodwa njengemveliso yempahla ekrwada yeyeza. Ukusuka kwinkangeleko, ibonakala njengekristale emhlophe. Lolona setyenziso luxhaphakileyo kushishino lwamayeza kwaye lunokuba isetyenziswa njengemathiriyeli ekrwada yeyeza, enefuthe elihle kakhulu ekuveliseni amachiza okulwa neentsholongwane ezibanzi.
Ixesha lokuposa: Jun-01-2023