Loluphi uhlobo lwechiza elisetyenziselwa ukunyanga i-cabazitaxel?

I-Cabazitaxel lichiza elisetyenziselwa ukunyanga umhlaza, okwiklasi yamachiza ebizwa ngokuba yi-"paclitaxel analogues". La machiza anokuthintela ukukhula kunye nokwahlukana kweeseli ze-tumor, ngaloo ndlela zicotha okanye zithintele ukuqhubeka komhlaza.

I-Cabazitaxel yaqala ukufunyanwa zizazinzulu kwi-National Cancer Institute e-United States.Emva kweminyaka yophando kunye nophuhliso, i-cabazitaxel iye yasetyenziswa ngokubanzi ichiza le-anticancer kwi-clinical practice.Ingasetyenziselwa ukunyanga iintlobo ezininzi zomhlaza, kubandakanywa nomhlaza webele, umhlaza we-ovarian, umhlaza wemiphunga weseli ongewona mncinci, umhlaza wedlala lobudoda, umhlaza wesisu, umhlaza wekholoni, njl.

Umgaqo wonyango wecabazitaxelkukuthintela ukukhula kunye nokwanda kweeseli ze-tumor ngokuphazamisa inkqubo yabo ye-Mitosis. Ngokukodwa, i-cabazitaxel inokudibanisa ne-Tubulin ukukhusela i-polymerization kunye ne-depolymerization ye-Tubulin, ngaloo ndlela ichaphazela inkqubo ye-Mitosis yeeseli ze-tumor, ezibangela ukuba iiseli zingakwazi ukwahlula. kwaye zande ngokuqhelekileyo, kwaye ekugqibeleni zikhokelela ekufeni kweseli yethumba.

Cabazitaxelliyeza elibalulekileyo le-anticancer elinika ithemba kunye namathuba kwizigulane ezininzi zokunyanga umhlaza.Ngenkqubela phambili eqhubekayo yesayensi kunye nobuchwepheshe, kukholelwa ukuba ukusebenza kunye nokhuseleko lwe-cabazitaxel luya kuphuculwa ngakumbi.

Ufundo olwandisiweyo: I-Hande Biotech igxile ekuvelisweni kwe-paclitaxel iminyaka emininzi, kwaye lishishini elizimeleyo lemveliso ye-paclitaxel yemathiriyeli ekrwada yezityalo ezikhupha amayeza e-anticancer avunywe ziiarhente zolawulo zelizwe ezifana ne-US FDA, i-EDQM yaseYurophu, i-Australian TGA, eTshayina. I-CFDA, i-India, iJapan, njl.njl uYunnan Hande ibonelela ngekhwalithi ephezuluCabazitaxelizixhobo ekrwada, ekhoyo kwi stock.Ukuba uyazifuna, nceda uzive ukhululekile ukuqhagamshelana nathi nangaliphi na ixesha.