I-Sophora flavescens ikhupha i-Sophoridine i-98% yezixhobo zokuthambisa

Ulwazi ngeMveliso

Isicatshulwa seSophora flavescens sisicatshulwa seSophora flavescens, isityalo esinemidumba.Umxholo we-oxymatrine, eyona nto isebenzayo, ingaphezulu kwe-98%.Inemisebenzi kunye nobuchule bokucoca ukushisa, ukomisa umswakama, ukubulala izinambuzane kunye ne-diuresis.Isetyenziselwa isifo segazi esishushu, isitulo esinegazi, i-jaundice, ukuvala umchamo, i-leucorrhea ebomvu, ukudumba kweYin, ukurhawuzelelwa yi-Yin, i-eczema, izilonda ezimanzi, ukukrala kwesikhumba, ukhwekhwe, iqhenqa, unyango lwangaphandle lwe-trichomonal vaginitis.
1, Amacandelo aphambili
I-Sophora flavescens extract iqulethe iindidi ze-alkaloids kunye ne-flavonoids.I alkaloids ikakhulu yi matrine kunye ne Oxymatrine, kunye ne dehydro matrine, d-sophoricine, 1-smelly bean base, 1-methylgenistein, 1-wild indigo leaf base, 1-sophora root base, njl. , isodehydrated icariin njalo njalo.
2. Umsebenzi
1. Ukukhuselwa kwe-mucosa yesisu
I-Sophora flavescens extract inefuthe elicacileyo lokukhusela kwi-gastric mucosal ukulimala okubangelwa yi-hydrochloric acid, i-ethanol kunye ne-indomethacin.Inxalenye yayo ephambili yi-flavanone compounds.
2. Isiphumo esichasene nokuvuvukala
I-Matrine inefuthe elicacileyo lokuchasana nokudumba kwi-acute exudative ukudumba okubangelwa zii-agent ezahlukeneyo zokudumba (ioli ye-croton, i-acetic acid ye-glacial, i-carrageenan kunye neqanda elimhlophe), elifana nelo le-hydrocortisone.Uphononongo lubonise ukuba le mveliso ineempawu ze-non-steroidal anti-inflammatory drugs.Ukongezelela, i-matrine inefuthe lokuzinzisa kwi-membrane ye-erythrocyte, kwaye iziyobisi ezinefuthe lokuzinza kwi-erythrocyte zihlala zinefuthe lokuzinza kwi-lysosomal membrane, ukwenzela ukunciphisa ukukhululwa kwabalamli abavuthayo kunye nokufezekisa injongo yokuchasana nokuvuvukala.
3. Impembelelo ye-Antitumor
I-Sophocarpine nayo inomsebenzi wokulwa nomhlaza.I-Matrine, i-Oxymatrine, i-sophocarpine kunye ne-mixed a, i-B kunye ne-C iziseko kwimilinganiselo eyahlukeneyo ibe nemiphumo eyahlukeneyo yokuthintela kwi-S180 i-tumor eqinile.I-Matrine inempembelelo ebalulekileyo yokuthintela kwisantya sokuveliswa kwekholoni yeeseli ze-peripheral multidirectional hematopoietic progenitor kwi-myeloid leukemia engapheliyo.I-Sophora flavescens decoction inokuphembelela ngokubonakalayo iiseli ze-leukemia ukuba zihluke kwi-monocyte macrophages xa isebenza kwiiseli ze-leukemia zabantu kwi-vitro.
4. I-leukocyte yokunyusa umphumo
I-Oxymatrine inokuthintela i-leukopenia kwiigundane ezibangelwa yi-MMC kunye ne-cyclophosphamide.Inaliti ye-intravenous okanye intramuscular of total Oxymatrine kunye ne-Oxymatrine inokunyusa kakhulu inani le-peripheral blood leukocytes kwimivundla eqhelekileyo.Ngaphezu koko, ixesha lesiphumo esibalulekileyo, ixesha lokugcinwa kunye nexabiso eliphezulu le-leukocyte count ye-oxymatrine kwimivundla eqhelekileyo ngokusisiseko iyafana phakathi kweentsuku ezili-18 emva kokulawulwa, Isiphumo sokwenza mhlophe singcono kuneso sotywala sesibindi sikakrebe.
5. Impembelelo kwi-cardiovascular system
Inaliti ye-intravenous ye-matrine kunye ne-Oxymatrine ichasene kakhulu ne-arrhythmias eyenziwa yi-aconitine kunye ne-chloroform adrenaline kwiigundane;Inaliti ye-Intraperitoneal ichasene kakhulu kwaye i-chloroform yenza i-fibrillation ye-ventricular kwiimpuku, yandisa idosi ye-aconitine eyenza i-arrhythmia kwiimpuku, kunye ne-arrhythmia echasayo eyenziwa yi-barium chloride kunye nokuxhunyaniswa kwe-coronary artery yangaphambili ehlayo kwiimpuku.
6. I-Antiasthmatic kunye ne-expectorant effect
I-Matrine ubukhulu becala nge-excitement β Receptors, ingakumbi i-excitatory center β Receptor, ikhupha i-bronchospasm kunye nokuthintela ukukhutshwa kwee-antibodies kunye nezinto ezicothayo ezisebenzayo.
7. Isiphumo sokuzinzisa
I-Matrine inokuthintela ngokubonakalayo ukuhamba ngokukhululekileyo kweempuku;Ithintele ngokubonakalayo umsebenzi owenziwayo weempuku;Idosi ephezulu inokuthintela ukulwa kunye nokuziphatha okundlongondlongo kweempuku ezilolo.
8. Impembelelo ye-Antifungal
I-Decoction ye-Sophora flavescens inefuthe elithintelayo kwi-fungi yesikhumba eqhelekileyo.
9. I-Bacteriostasis
Isicatshulwa se-Sophora flavescens sinokunqanda i-Staphylococcus, i-Pseudomonas aeruginosa kunye ne-Mycobacterium tuberculosis.
10. Impembelelo kwinkqubo ye-nervous central
Xa i-matrine yayitofelwe kwimivundla, kwafunyanwa ukukhubazeka kwemithambo-luvo ephakathi, kwabakho ukuqhawuka kwemithambo ngaxeshanye, kwaye ekugqibeleni ukuphefumla kwema kwaye kwafa.Xa ifakwe kwisele, iqala ibe nemincili, emva koko ikhubazeke, kwaye ukuphefumla kuyacotha kwaye kungaqhelekanga.Kamva, i-spasm iyenzeka, ekhokelela ekubanjweni kokuphefumla kunye nokufa.Ukuhlaselwa kwe-spasm mhlawumbi kubangelwa yi-hyperreflexia yentambo yomgogodla.
11. Impembelelo ye-Antiarrhythmic
I-Sophora flavescens inefuthe elihle elichasayo kwi-arrhythmia ebangelwa yi-aconitine, i-amine enovelwano kunye ne-digitalis poisoning, kwaye isiphumo sayo siyafana ne-quinidine.Oko kukuthi, ngokuchaphazela inkqubo ye-potassium kunye ne-sodium conduction ye-membrane ye-cardiomyocyte, ixesha elichasayo le-myocardium lide kwaye uxinzelelo luyancitshiswa, ukwenzela ukuba inqanda i-ectopic pacemaker kwaye idlale indima ye-anti arrhythmia.Isithako esisebenzayo ekuqaleni kwangqinwa ukuba yinxalenye yealkaloid.Ngenxa yokuba i-Sophora flavescens ayinayo impembelelo kwi-contractility ye-myocardial kunye nesantya sentliziyo ye-frog kwi-vivo kunye neempuku, ayinyusi ukusetyenziswa kwe-oksijini ye-myocardial kwaye ikhulise ukungaphumeleli kwentliziyo kunye nomothuko, ofanelwe ingqalelo kwisifo senhliziyo ye-ischemic.
3, Indawo yosetyenziso
1. Umzi-mveliso wamachiza: usetyenziselwa ukutshisa, i-blood stool, i-jaundice, i-dysuria, i-leucorrhea ebomvu, i-Yin ukudumba kunye ne-Yin ukurhawuzelela, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-eczema, i-skin, i-scabies, iqhenqa, unyango lwangaphandle lwe-trichomonal vaginitis.
2. Imboni yezithambiso: Isicatshulwa se-Sophora flavescens sine-whitening, anti-inflammatory, anti-acne, antibacterial kunye nezinye iziphumo.Isetyenziswe kubuhle kunye nokunyamekela ulusu kwasekuqaleni kumakhulu eminyaka eyadlulayo.Ngoku iyeyona nto ithandwayo yokuthambisa yezixhobo zokuthambisa eziphambili.

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