Umzi-mveliso we-GMP uthengisa umxholo ophezulu kunye nokucoceka okuphezulu kwe-10-DAB Semi-synthetic Paclitaxel

Ulwazi ngeMveliso

Igama:10-DAT Semi-synthetic Paclitaxel

Inombolo yeCAS:33069-62-4

Ifomula yemichiza:C47H51NO14

Iinkcukacha:99%-102%

Umbala:umgubo omhlophe okanye phantse omhlophe

Umthombo:Taxus yunnanensis,Taxus chinensis

Uhlobo:APIs

Iziphumo kunye neenzuzo

I-Anticancer effect: I-10-DAB semi-synthetic paclitaxel inefuthe elinamandla le-anticancer, elinokuthi lithintele ngokufanelekileyo ukukhula kunye nokusasazeka kweeseli ze-tumor kwaye zenze i-apoptosis ye-tumor cell. umsebenzi kunye ne-anticancer spectrum ebanzi.

I-2.Ukhuseleko: I-10-DAB i-semi-synthetic paclitaxel kwi-design kunye nenkqubo yokuvelisa, kugxininise ekuphuculeni ukhuseleko lwemveliso kunye nokunyamezela.Ngokuguqula kunye nokuphucula ukwakheka kweekhemikhali ze-paclitaxel yendalo, iziganeko zemiphumo emibi kunye neempembelelo ezimbi zancitshiswa.

I-3.Izakhiwo ze-Pharmacokinetic: I-10-DAB i-semi-synthetic paclitaxel ineempawu ezingcono ze-pharmacokinetic, ukwenzela ukuba ikwazi ukuxutywa kakuhle kwaye isasazwe emzimbeni, ngaloo ndlela iphucula umphumo wonyango.

I-4.Ukusetyenziswa: I-10-DAB semi-synthetic paclitaxel ingasetyenziselwa ukunyanga iintlobo ezahlukeneyo zomhlaza, kubandakanywa nemiphunga, isifuba, i-ovarian, isisu, kunye nokunye.Ukusebenza kwayo kunye nokhuseleko luye lwaqinisekiswa ngokubanzi kwiklinikhi.

Iinkonzo zethu

1.Iimveliso:Ukubonelela ngomgangatho ophezulu, izicatshulwa zezityalo ezisulungekileyo, imathiriyeli ekrwada yamayeza, kunye nabaphakathi bamayeza.

2.Iinkonzo zobugcisa:Izicatshulwa ezenziwe ngokwezifiso ezineenkcazo ezizodwa ngokweemfuno zabathengi.