Umgangatho ophezulu we-Indole-3-carbinol CAS 700-06-1

Ulwazi ngeMveliso

Igama:Indole-3-carbinol

Isiteketiso:indole-3-methane

Inombolo yeCAS:700-06-1

Ifomula yemichiza:C9H9NO

Ubume bemolekyuli:

Inkcazo:99% HPLC

Umbala:umgubo omhlophe

Isiphumo

I-1, uthintelo lomhlaza: I-I3C ithathwa njengendima ekuthinteleni umhlaza, ngakumbi ngezi ndlela zilandelayo: ukwenza buthathaka isiphumo se-estrogen, ukunciphisa umphumo wokukhuthaza ukwanda kweeseli; Ukuthintela ngokuyinxenye umphumo we-estrogen kwiiseli ezijoliswe kuyo; Ukubulala okanye ukuvimbela ngokuthe ngqo. iiseli zethumba; Nciphisa amanqanaba eradical yasimahla, thintela umonakalo weDNA, kwaye unciphise umngcipheko womhlaza.

I-2, ibhalansi ye-hormone: I-I3C inokunceda ukugcina ibhalansi ye-endocrine, ngakumbi kulawulo lwe-estrogen.Izifundo zokuqala zibonise ukuba i-I3C inokuxhasa isibindi ukuthotywa kwe-estrogen engaphezulu.

3, impilo yamathumbu: Uphononongo lufumene ukuba i-I3C inokusebenza kwi-receptors ye-hydrocarbon enevumba elimnandi yeeseli zamathumbu, ilawule umqobo wamathumbu kunye nokusebenza kwamathumbu emathunjini. Ukuvuvukala.Ukusebenza okunengqiqo kwe-aromatics hydrocarbon receptor (efana ne-I3C) inokukhuthaza ukulungiswa kwesithintelo samathumbu kwaye inqanda i-carcinogenesis yeeseli ze-epithelial zamathumbu.Ukongezelela, i-I3C inokubangela ukuveliswa kwe-IL-22 kunye neeseli ze-T ezilawulayo, kwaye inhibit. Iiseli ze-Th17, ngaloo ndlela zinciphisa impendulo yokuvuvukala kwamathumbu.

I-4, inkxaso yokusebenza kwesibindi: izifundo zibonise ukuba i-I3C inefuthe elithile lokukhusela kwisibindi.

Iinkonzo zethu

1.Iimveliso:Ukubonelela ngomgangatho ophezulu, izicatshulwa zezityalo ezisulungekileyo, imathiriyeli ekrwada yamayeza, kunye nabaphakathi bamayeza.

2.Iinkonzo zobugcisa:Izicatshulwa ezenziwe ngokwezifiso ezineenkcazo ezizodwa ngokweemfuno zabathengi.